|
The dopamine hypothesis is the oldest and most established of the schizophrenia hypotheses. It has evolved from clinical observations, and received empirical validation from antipsychotic treatment and more direct testing from imaging studies. Although clearly not sufficient to explain the complexity of this disorder, it offers a direct relationship to symptoms and to their treatment.Bottom Line: The idea that the symptoms of psychosis or schizophrenia are caused by the overactivity of dopamine is not supported by current evidence. |
